Medical and Clinical Laboratory Technologist Salary in Sioux Falls, SD: $63,251 (2026)
Quick Answer:A full-time medical and clinical laboratory technologist in Sioux Falls, SD earns a median $63,251/year (≈ $30.41/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-2010). Once you factor in Sioux Falls's price level (9% below national, BEA RPP 90.6), that paycheck buys what $69,790 would nationally. Nominal pay sits 6.4% below the South Dakota state average.
Official BLS data · View source
In Sioux Falls, SD, the market for medical and clinical laboratory technologists remains promising, with an estimated employment of around 650 professionals in this field. The projected median annual salary stands at $63,251, reflecting a competitive position compared to many other regions. Salary ranges for these technologists vary significantly, with figures from $34,994 at the lower end (P10) to $88,612 at the top (P90). This data is derived from official Bureau of Labor Statistics (BLS) OEWS surveys, which indicate both a healthy demand for these roles and a scope for specialized practice to influence earning potential. For those considering this career path, the relatively high employment count in Sioux Falls suggests a stable job market, while salaries reflect the area's economic conditions.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $34,994 | $16.83 |
| Lower Range (P25) | $51,487 | $24.75 |
| Median (P50)(typical) | $63,251 | $30.41 |
| Upper Range (P75) | $85,030 | $40.89 |
| Top Earners (P90) | $88,612 | $42.60 |
Median Salary Position
7.98% below the national average
2026 Salary Percentile Distribution in Sioux Falls
In Sioux Falls, SD, the medical and clinical laboratory technologist salary spread from the 10th to 90th percentile is $53,618 (2026 est.). At $63,251, the local median is 7.98% below the national median of $68,734.
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At 40 hours/week in Sioux Falls: You'd be above the median
How Sioux Falls Medical and Clinical Laboratory Technologist Pay Compares
Sioux Falls median: $63,251/year (2026)
| Compared To | Median Salary | Sioux Falls Pays |
|---|---|---|
| South Dakota Average | $67,576 | -6.40% less |
| National Average | $68,734 | -7.98% less |
Medical and Clinical Laboratory Technologists in Sioux Falls, SD earn a median of $63,251 per year (2026 est.), which is 7.98% lower than the national median of $68,734 and 6.40% below the South Dakota state average of $67,576.
Cost-of-Living Adjusted Salary
Sioux Falls has a cost of living 9.37% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Sioux Falls, SD has a cost-of-living index of 90.631 (below the national average of 100). A medical and clinical laboratory technologist earning $63,251 nominally has purchasing power equivalent to $69,790 in an average-cost city — an effective 10.34% boost.
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2019 BLS Actual
$48,780
2025 BLS Actual
$61,385
2026 Current Est.
$63,251
2019–2027 Growth
+33.6%
Salary Trajectory for Medical and Clinical Laboratory Technologists in Sioux Falls (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.04% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $48,780 | Actual |
| 2020 | $49,620 | Actual |
| 2021 | $47,380 | Actual |
| 2022 | $48,470 | Actual |
| 2023 | $52,870 | Actual |
| 2024 | $55,870 | Actual |
| 2025 | $61,385 | Actual |
| 2026(current) | $63,251 | Estimated |
| 2027 | $65,174 | Projected |
Based on 7 years of BLS OEWS data for the Sioux Falls metropolitan area, the median medical and clinical laboratory technologist salary grew 25.8% from $48,780 (2019) to $61,385 (2025). At a 3.04% compound annual growth rate, salaries are projected to reach $65,174 by 2027 — a total increase of $16,394 (33.61%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Sioux Falls metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.04% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $34,994 – $51,487 |
| 3-5 years (Mid Career) | $51,487 – $63,251 |
| 5+ years (Experienced) | $63,251 – $85,030 |
| 10+ years (Top Earner) | $85,030 – $88,612 |
MLS salary ranges estimated from BLS percentile data. Individual medical and clinical laboratory technologist compensation varies by employer, certifications, and specialization.
Medical and Clinical Laboratory Technologist Job Market in Sioux Falls
The salary landscape for medical and clinical laboratory technologist pay in Sioux Falls SD is influenced by several factors, including the cost of living, which is indexed at 90.631, below the national average. This lower cost of living enhances the take-home purchasing power of local technologists, making their compensation more attractive. Employers such as large healthcare organizations typically offer the highest salaries compared to private practices, community health centers, and specialty clinics, driven by the scale of operations and the breadth of services provided. Variability in pay also arises from factors such as shift differentials, specialty credentials, and the overall benefits structure afforded by employers. For those looking to maximize their pay, obtaining advanced certifications or taking on shifts with more demanding hours can make a significant difference in overall compensation within the Sioux Falls market.
More salary data for Sioux Falls, SD:
Frequently Asked Questions
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Written by Alexandra Choi, MS, MT(ASCP)
Career Analyst
Alexandra has 10 years of experience in clinical laboratory science. She specializes in molecular diagnostics. She works at a large metropolitan hospital.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $61,385 for medical and clinical laboratory technologistsin the Sioux Falls metropolitan area. A 3.04% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.04%, derived from historical BLS wage trends for medical and clinical laboratory technologists (SOC 29-2010).
Compiled and verified by Alexandra Choi, MS, MT(ASCP), a licensed medical and clinical laboratory technologist with 10+ years of clinical experience. · View source data at BLS.gov