Medical and Clinical Laboratory Technologist Salary in Palmdale, CA: $77,201 (2026)
Quick Answer:A full-time medical and clinical laboratory technologist in Palmdale, CA earns a median $77,201/year (≈ $37.12/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-2010). Once you factor in Palmdale's price level (13% above national, BEA RPP 113.1), that paycheck buys what $68,259 would nationally. Nominal pay sits 0.6% below the California state average.
Based on BLS state-level estimates · View source

In Palmdale, California, the projected median salary for medical and clinical laboratory technologists in 2026 is $77,201, offering a competitive edge compared to the national median of $68,734. The salary distribution reflects a notable range, with entry-level positions earning around $48,062, while seasoned professionals can earn as much as $119,661. These figures represent local estimates based on 2025 BLS data, including adjustments for the cost of living in the region, which stands at 113.1—above the national average. With only 29 medical and clinical laboratory technologists currently employed in Palmdale, job saturation is lower, suggesting a potentially favorable job market for those entering the field.
About the Palmdale Market
Salary estimated from California average ($100,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $48,062 | $23.11 |
| Lower Range (P25) | $58,324 | $28.04 |
| Median (P50)(typical) | $77,201 | $37.12 |
| Upper Range (P75) | $98,816 | $47.51 |
| Top Earners (P90) | $119,661 | $57.53 |
Median Salary Position
12.32% above the national average
2026 Salary Percentile Distribution in Palmdale
In Palmdale, CA, the medical and clinical laboratory technologist salary spread from the 10th to 90th percentile is $71,599 (2026 est.). At $77,201, the local median is 12.32% above the national median of $68,734.
Salary Calculator
At 40 hours/week in Palmdale: You'd be in the lower-middle range
How Palmdale Medical and Clinical Laboratory Technologist Pay Compares
Palmdale median: $77,201/year (2026)
| Compared To | Median Salary | Palmdale Pays |
|---|---|---|
| California Average | $77,667 | -0.60% less |
| National Average | $68,734 | +12.32% more |
Medical and Clinical Laboratory Technologists in Palmdale, CA earn a median of $77,201 per year (2026 est.), which is 12.32% higher than the national median of $68,734 and 0.60% below the California state average of $77,667.
Cost-of-Living Adjusted Salary
Palmdale has a cost of living 13.10% above the national average.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Palmdale, CA has a cost-of-living index of 113.1 (above the national average of 100). While the nominal salary of $77,201 is competitive, the higher cost of living reduces purchasing power to an effective $68,259 — a 11.58% reduction.
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2019 BLS Actual
$63,243
2025 BLS Actual
$74,923
2026 Current Est.
$77,201
2019–2027 Growth
+25.8%
Salary Trajectory for Medical and Clinical Laboratory Technologists in Palmdale (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.04% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $63,243 | Actual |
| 2020 | $64,505 | Actual |
| 2021 | $68,815 | Actual |
| 2022 | $68,315 | Actual |
| 2023 | $72,363 | Actual |
| 2024 | $112,380 | Actual |
| 2025 | $74,923 | Actual |
| 2026(current) | $77,201 | Estimated |
| 2027 | $79,548 | Projected |
Based on 7 years of BLS OEWS data for the Palmdale metropolitan area, the median medical and clinical laboratory technologist salary grew 18.5% from $63,243 (2019) to $74,923 (2025). At a 3.04% compound annual growth rate, salaries are projected to reach $79,548 by 2027 — a total increase of $16,305 (25.78%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Palmdale metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.04% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $48,062 – $58,324 |
| 3-5 years (Mid Career) | $58,324 – $77,201 |
| 5+ years (Experienced) | $77,201 – $98,816 |
| 10+ years (Top Earner) | $98,816 – $119,661 |
MLS salary ranges estimated from BLS percentile data. Individual medical and clinical laboratory technologist compensation varies by employer, certifications, and specialization.
Medical and Clinical Laboratory Technologist Job Market in Palmdale
Compensation for medical and clinical laboratory technologists in Palmdale is influenced by several key factors, primarily the type of employer. Positions within large healthcare organizations and specialty clinics often provide higher compensation compared to private practices and community health centers. This variance stems from factors such as shift differentials and the necessity for advanced credentials in specialized areas. With a cost-of-living index higher than the national average, take-home pay can be impacted, making it crucial for professionals to negotiate their salaries and seek positions that maximize benefits. To enhance earning potential in the Palmdale market, pursuing additional certifications and considering opportunities in larger healthcare systems may lead to increased compensation, aligning pay more closely with the area's cost of living dynamics.
More salary data for Palmdale, CA:
Frequently Asked Questions
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Written by Alexandra Choi, MS, MT(ASCP)
Career Analyst
Alexandra has 10 years of experience in clinical laboratory science. She specializes in molecular diagnostics. She works at a large metropolitan hospital.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $74,923 for medical and clinical laboratory technologistsin the Palmdale metropolitan area. A 3.04% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Palmdale is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.04%, derived from historical BLS wage trends for medical and clinical laboratory technologists (SOC 29-2010).
Compiled and verified by Alexandra Choi, MS, MT(ASCP), a licensed medical and clinical laboratory technologist with 10+ years of clinical experience. · View source data at BLS.gov