San Francisco vs Santa Maria: Medical and Clinical Laboratory Technologist Salary (2026)
Compare medical and clinical laboratory technologist salaries between San Francisco, CA and Santa Maria, CA. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | San Francisco, CA | Santa Maria, CA |
|---|---|---|
| Median Salary | $91,889▲ | $58,586 |
| Hourly Rate | $44.18▲ | $28.17 |
| Entry Level (P10) | $60,695▲ | $53,158 |
| 25th Percentile | $74,064▲ | $55,278 |
| 75th Percentile | $105,749▲ | $74,763 |
| Top Earner (P90) | $145,987▲ | $100,048 |
| Total Employed | 5,210▲ | 240 |
Verdict
San Francisco, CA offers better overall compensation for medical and clinical laboratory technologists, winning 4 out of 4 metrics compared to Santa Maria.
The salary gap between San Francisco and Santa Maria is $33,303 (56.84%). San Francisco's median is +33.69% compared to the US national median of $68,734.
Salary Range Comparison
The full salary range (10th to 90th percentile) in San Francisco spans $85,292,Santa Maria spans $46,890. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, San Francisco ($79,480 effective) pays 47.60% more than Santa Maria ($53,848 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose San Francisco if…
- ✓Higher median salary ($91,889/year)
- ✓Better top-earner potential ($145,987)
- ✓Larger job market (5,210 employed)
- ✓Better purchasing power (CoL-adjusted: $79,480)
- ✓You prefer the California area and lifestyle
Choose Santa Maria if…
- ✓You prefer the California area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, medical and clinical laboratory technologist salaries in San Francisco grew 39.3% from 2019 to 2025, compared to -12.2% growth in Santa Maria over the same period.
San Francisco, CA
$64,010 (2019) → $89,178 (2025)
Santa Maria, CA
$64,790 (2019) → $56,858 (2025)
View Full Salary Data
San Francisco, CA
Santa Maria, CA
Frequently Asked Questions
Which city pays medical and clinical laboratory technologists more: San Francisco or Santa Maria?
What is the hourly rate difference between San Francisco and Santa Maria?
Should I relocate from San Francisco to Santa Maria as a medical and clinical laboratory technologist?
What do entry-level medical and clinical laboratory technologists earn in San Francisco vs Santa Maria?
Related Comparisons
Written by Alexandra Choi, MS, MT(ASCP)
Career Analyst
Alexandra has 10 years of experience in clinical laboratory science. She specializes in molecular diagnostics. She works at a large metropolitan hospital.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.04% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Choi, MS, MT(ASCP), a licensed medical and clinical laboratory technologist with 10+ years of clinical experience. · View source data at BLS.gov