San Diego vs San Mateo: Medical and Clinical Laboratory Technologist Salary (2026)
Compare medical and clinical laboratory technologist salaries between San Diego, CA and San Mateo, CA. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | San Diego, CA | San Mateo, CA |
|---|---|---|
| Median Salary | $69,651 | $78,520▲ |
| Hourly Rate | $33.49 | $37.75▲ |
| Entry Level (P10) | $49,292▲ | $45,542 |
| 25th Percentile | $55,332 | $60,887▲ |
| 75th Percentile | $88,077 | $100,505▲ |
| Top Earner (P90) | $139,488▲ | $121,706 |
| Total Employed | 2,740▲ | 21 |
Verdict
San Diego and San Mateo are closely matched on overall medical and clinical laboratory technologist compensation, each winning on different metrics.
The salary gap between San Diego and San Mateo is $8,869 (12.73%). San Mateo's median is +14.24% compared to the US national median of $68,734.
Salary Range Comparison
The full salary range (10th to 90th percentile) in San Diego spans $90,196,San Mateo spans $76,164. San Diego has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, San Mateo ($69,425 effective) pays 11.52% more than San Diego ($62,251 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose San Diego if…
- ✓Better top-earner potential ($139,488)
- ✓Larger job market (2,740 employed)
- ✓You prefer the California area and lifestyle
Choose San Mateo if…
- ✓Higher median salary ($78,520/year)
- ✓Better purchasing power (CoL-adjusted: $69,425)
- ✓You prefer the California area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, medical and clinical laboratory technologist salaries in San Diego grew 17.7% from 2019 to 2025, compared to -33.3% growth in San Mateo over the same period.
San Diego, CA
$57,410 (2019) → $67,596 (2025)
San Mateo, CA
$114,300 (2024) → $76,203 (2025)
View Full Salary Data
San Diego, CA
San Mateo, CA
Frequently Asked Questions
Which city pays medical and clinical laboratory technologists more: San Diego or San Mateo?
What is the hourly rate difference between San Diego and San Mateo?
Should I relocate from San Diego to San Mateo as a medical and clinical laboratory technologist?
What do entry-level medical and clinical laboratory technologists earn in San Diego vs San Mateo?
Related Comparisons
Written by Alexandra Choi, MS, MT(ASCP)
Career Analyst
Alexandra has 10 years of experience in clinical laboratory science. She specializes in molecular diagnostics. She works at a large metropolitan hospital.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.04% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Choi, MS, MT(ASCP), a licensed medical and clinical laboratory technologist with 10+ years of clinical experience. · View source data at BLS.gov