Med Lab Scientist Salary

Mission Viejo vs San Francisco: Medical and Clinical Laboratory Technologist Salary (2026)

Compare medical and clinical laboratory technologist salaries between Mission Viejo, CA and San Francisco, CA. All figures are 2026 estimates projected from BLS 2025 data.

Mission Viejo, CA
$78,417
$37.70/hr
San Francisco, CA
$91,889
$44.18/hr

Side-by-Side Comparison

MetricMission Viejo, CASan Francisco, CA
Median Salary$78,417$91,889
Hourly Rate$37.70$44.18
Entry Level (P10)$48,079$60,695
25th Percentile$58,484$74,064
75th Percentile$100,225$105,749
Top Earner (P90)$121,546$145,987
Total Employed235,210
Side-by-side bar chart comparing Mission Viejo ($78,417) and San Francisco ($91,889) medical and clinical laboratory technologist salaries.Mission ViejoSan FranciscoMedian Salary$78,417$91,889Entry Level (P10)$48,079$60,695Top Earner (P90)$121,546$145,987US Median $68,734

Verdict

San Francisco, CA offers better overall compensation for medical and clinical laboratory technologists, winning 4 out of 4 metrics compared to Mission Viejo.

The salary gap between Mission Viejo and San Francisco is $13,472 (17.18%). San Francisco's median is +33.69% compared to the US national median of $68,734.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Mission Viejo spans $73,467,San Francisco spans $85,292. San Francisco has a wider pay range, suggesting more variation in pay between entry-level and experienced medical and clinical laboratory technologists.

Mission Viejo
P10 (Entry)$48,079
P25$58,484
Median$78,417
P75$100,225
P90 (Top)$121,546
San Francisco
P10 (Entry)$60,695
P25$74,064
Median$91,889
P75$105,749
P90 (Top)$145,987

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($79,480 effective) pays 14.63% more than Mission Viejo ($69,334 effective).

Mission Viejo
Nominal: $78,417
CoL Index: 113.1
Adjusted: $69,334
San Francisco
Nominal: $91,889
CoL Index: 115.613
Adjusted: $79,480

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Mission Viejo if…

  • You prefer the California area and lifestyle

Choose San Francisco if…

  • Higher median salary ($91,889/year)
  • Better top-earner potential ($145,987)
  • Larger job market (5,210 employed)
  • Better purchasing power (CoL-adjusted: $79,480)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, medical and clinical laboratory technologist salaries in Mission Viejo grew -33.3% from 2024 to 2025, compared to 39.3% growth in San Francisco over the same period.

Mission Viejo, CA

+-33.3%

$114,150 (2024) → $76,103 (2025)

San Francisco, CA

+39.3%

$64,010 (2019) → $89,178 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays medical and clinical laboratory technologists more: Mission Viejo or San Francisco?

San Francisco has a higher median medical and clinical laboratory technologist salary at $91,889/year, compared to Mission Viejo at $78,417/year — a difference of $13,472 (17.18%).

What is the hourly rate difference between Mission Viejo and San Francisco?

Mission Viejo medical and clinical laboratory technologists earn $37.70/hr while San Francisco hygienists earn $44.18/hr (2026 est.).

Should I relocate from Mission Viejo to San Francisco as a medical and clinical laboratory technologist?

Consider more than just salary when comparing Mission Viejo and San Francisco. Factor in cost of living (CoL-adjusted: Mission Viejo = $69,334, San Francisco = $79,480), job availability (23 vs 5,210 employed), commute, and career growth potential.

What do entry-level medical and clinical laboratory technologists earn in Mission Viejo vs San Francisco?

Entry-level (10th percentile) medical and clinical laboratory technologists earn $48,079 in Mission Viejo and $60,695 in San Francisco. The San Francisco area offers higher starting salaries.

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Written by Alexandra Choi, MS, MT(ASCP)

Career Analyst

Alexandra has 10 years of experience in clinical laboratory science. She specializes in molecular diagnostics. She works at a large metropolitan hospital.

Clinically reviewed by Jerome Patel, BS, MT(ASCP)Data verified by Fatima Hussain, MS, CLS

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.04% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Choi, MS, MT(ASCP), a licensed medical and clinical laboratory technologist with 10+ years of clinical experience. · View source data at BLS.gov